Bless you

It first stared during the plague of AD 590. That if they sneezed they must be immediately be blessed 

(god bless you) since sneezing was often the first sign that someone was falling ill.

This originated during the plague of AD 590.

It originated in plague of AD 590 whenever someone sneezed they must immediately say “god bless you” and then it became customary.

This originated in central Asia.